Polynucleotide

lastmod: 2026-03-29

What Is Polynucleotide Treatment?

Polynucleotide treatment is a regenerative injectable therapy that uses purified DNA fragments to stimulate your skin’s natural repair processes. Unlike dermal fillers that add volume, or botulinum toxin that relaxes muscles, polynucleotides work at a cellular level to improve the fundamental quality of your skin.

When injected, polynucleotides create a favourable environment for tissue regeneration. They attract and retain water molecules for deep hydration, support fibroblast activity to boost collagen and elastin production, and provide antioxidant protection against environmental damage. The result is skin that looks healthier, feels firmer, and ages more gracefully.

What Does It Treat?

• Ageing skin – Restores firmness, elasticity, and resilience
• Dehydrated skin – Provides deep, lasting hydration from within
• Fine lines and wrinkles – Smooths early signs of ageing through collagen stimulation
• Loss of elasticity – Improves skin bounce and tone
• Dull complexion – Promotes cell renewal for a fresher appearance
• Sun-damaged skin – Supports repair of UV-exposed tissue
• Crepey skin – Strengthens thin, fragile skin on the face, neck, or décolletage
• Under-eye concerns – Improves skin quality in delicate areas
• Scarring – Can support tissue remodelling as part of a combined treatment plan

Why Polynucleotide Treatment at Lux Clinic?

Evidence-Based Regenerative Medicine

Polynucleotide treatments are backed by a growing body of clinical research. At Lux Clinic, we use established, clinically validated polynucleotide products—not experimental or unproven formulations.

Personalised Protocols

Polynucleotide treatment is a category of treatment with several available preparations, each suited to different concerns and areas. During your consultation, we assess your skin condition and treatment goals to select the most appropriate product and protocol.

Complementary Treatment Options

Polynucleotide therapy integrates well with other treatments. Many clients combine it with Plinest for targeted skin quality improvement, PRP treatment for enhanced regenerative effects, or Lumi Pro for focused under-eye rejuvenation. We will advise on the best combination based on your individual assessment.

What to Expect

Your Consultation

Your practitioner will evaluate your skin quality, discuss the areas you would like to treat, and explain which polynucleotide product and protocol best suits your needs. We take time to set realistic expectations—this is a regenerative treatment that works gradually, and we want you to understand the timeline before committing.

The Treatment (30-45 minutes)

1. Cleansing – The treatment area is prepared and cleaned
2. Numbing – A topical anaesthetic is applied for comfort
3. Injection – Polynucleotides are administered using fine needles across the treatment area
4. Distribution – Gentle massage ensures even product placement where appropriate
5. Aftercare – Soothing products are applied and aftercare guidance provided

Treatment can be performed on the face, neck, décolletage, and hands where skin quality improvement is desired.

After Your Treatment

• Mild swelling, redness, or small papules at injection sites are normal and typically resolve within 24-48 hours
• Avoid touching the treated area, strenuous exercise, saunas, and alcohol for 24 hours
• Apply SPF 30+ daily to protect the treated skin
• A course of 3-4 sessions, spaced 2-4 weeks apart, is typically recommended
• Maintenance sessions every 3-6 months help sustain results
• Improvements develop gradually as your skin regenerates from within

Pricing

From £250 per session

A course of 3-4 sessions is typically recommended for optimal results. Package pricing available—discuss options during your consultation.

Frequently Asked Questions

How is polynucleotide treatment different from fillers? Polynucleotides do not add volume or change your facial shape. They improve skin quality by stimulating your body’s own regenerative processes. Think of fillers as restoring lost structure, while polynucleotides restore lost skin health. The two can complement each other beautifully, but they serve different purposes.

How many sessions will I need? A typical course consists of 3-4 sessions spaced 2-4 weeks apart. After the initial course, maintenance sessions every few months help preserve the improvements. Your practitioner will recommend a specific schedule based on your skin condition and goals.

Is there any downtime? Very little. Expect mild redness and possible small bumps at the injection points, which usually settle within 24-48 hours. Most clients return to their normal routine straight away. We advise avoiding heavy exercise and direct sun exposure for the first day or two.

When will I see results? Polynucleotide treatment works gradually as your skin regenerates. Some clients notice improved hydration and texture within the first week, but the full effect develops over 4-8 weeks as new collagen and elastin form. This is a treatment that rewards patience—the results are worth the wait.

Can polynucleotide treatment be combined with other procedures? Yes, and it often is. Polynucleotides work particularly well alongside PRP treatment for a comprehensive regenerative approach, or with Plinest for enhanced skin quality outcomes. We will recommend the right combination during your consultation.